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KMID : 1098420050130060213
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Korean Journal of Medicinal Crop Science
2005 Volume.13 No. 6 p.213 ~ p.216
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Screening and Extraction Condition of Anti-skin Aging Elastase Inhibitor from Medicinal Plants
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Kwak Yoon-Jin
Lee Dae-Hyoung
Kim Na-Mi
Lee Jong-Soo
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Abstract
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To develop a new anti-skin aging cosmetics or functional foods by using elastase inhibitor, a potent elastase inhibitor was screened from various extracts of medicinal plants and its optimal extraction condition was investigated. Methanol extracts of Rubi fructus showed the highest elastase inhibitory activity of 85%. The elastase inhibitor of Rubi fructus was maximally extracted when it was treated with 80% methanol at 50^{circ}C for 12hr and its elastase inhibitory activity (IC_{50}) was 0.52 mg.
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KEYWORD
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anti-skin aging cosmetics, Rubi fructus, elastase inhibitor
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